新潟医療福祉大学

医療技術学部

Department of Clinical Engineering and Medical Technology 臨床技術学科

教員紹介

医療技術学部／臨床技術学科
Faculty of Medical Technology／Department of Clinical Engineering and Medical Technology

中川　沙織 Saori NAKAGAWA

教授

プロフィール

担当科目	薬理学、生化学検査学実習Ⅰ，Ⅱ、基礎ゼミ、連携基礎ゼミ
専門分野	臨床化学、分析化学、薬毒物分析
学位・称号／取得機関／取得年	博士（医学）／新潟大学大学院／2005
資格	1999 薬剤師免許証 2017 認定臨床化学者
所属団体・学会等	日本臨床化学会、生物試料分析科学会、日本分析化学会、医用マススペクトル学会、日本薬学会、クロマトグラフィー科学会

外部リンク

業績等

研究領域	コレステロール合成・吸収・代謝物の定量法の開発とその臨床応用
受賞歴	1. 2012 平成24年度（第14回）日本臨床化学会学会賞　奨励賞 2. 2016 第26回生物試料分析科学会年次学術集会優秀発表賞 3. 2017 第26回生物試料分析科学会年次学術集会優秀演題賞 4. 2022 2022年度　日本分析化学会関東支部新世紀賞 5. 2023 2023年度　日本臨床化学会学会賞　学術賞 6. 2023 第34回生物試料分析科学会年次学術集会優秀演題賞 7. 2023 Top Cited Article　2022-2023 8. 2024 女性Analyst賞 9. 2024 にいがた健活アワード2024　個人の部　特別賞
研究論文（英文）	1. Daisuke Tomita, Yuuki Bamba, Naoko Kuwabara, Shota Akakabe, Yasuhiro Matsubayashi, Saori Nakagawa, Hirohito Sone, and Kei Nishiyama A Case of Concurrent Metformin-Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis. Journal of Emergency Medicine 2025年2月 inpress 2. Naoko Kuwabara, Junkichi Kanda, Shinji Sato, Saori Nakagawa Impact of daily high ergosterol intake for 14 weeks in ovariectomized rats on cholesterol and vitamin D3 biosynthesis pathways. Biol. Pharm. Bull. 2024年12月 48(1),pp.39-45 3. Yusuke Mochizuki, Nagaaki Katoh, Akira Matsushima, Masahide Yazaki, Naoko Kuwabara, Saori Nakagawa, Yoshiki Sekijima Involvement of bile acid in diarrhea and therapeutic effect of colestimide in hereditary ATTR amyloidosis. Amyloid 2024年11月 32(1),pp.39-45 4. Naoko Kuwabara, Shinji Sato, Saori Nakagawa Effects of long-term high-ergosterol intake on the cholesterol and vitamin D biosynthetic pathways of rats fed a high-fat and high-sucrose diet. Biol. Pharm. Bull. 2023年12月 46(12),pp.1683-1691 5. Naoko Kuwabara, Fumiko Fuwa, Shinji Sato, Satoshi Hirayama, Takashi Miida, Saori Nakagawa Simultaneous determination of cholesterol precursors, plant sterols, and oxysterols in plasma using one-round pretreatment. Medical Mass Spectrometry 2023年6月 7(1),pp.89-97 6. Naoko Kuwabara, Shinji Sato, Masami Tsugita, Noriyasu Sato, Saori Nakagawa Effects of enteral formulas and their food protein and dietary fiber components on postprandial plasma warfarin concentration in rats. Chromatography 2023年5月 44(2),pp.69-76 7. Kai T, Hirayama S, Soda S, Fuwa F, Nakagawa S, Ueno T, Hori A, Miida T. Higher concentration of 25-hydroxycholesterol in treatment-naïve patients with type 2 diabetes compared to healthy individuals. J Clin Lipidol 2023年4月 17,384-391 8. Yusuke Sano, Naoko Kuwabara, Saori Nakagawa, Yuki Toda, Shigekuni Hosogi, Shinji Sato, Eishi Ashihara Hypoxia-adapted multiple myeloma stem cells resist γδ-T-cell-mediated killing by modulating the mevalonate pathway. Anticancer Research 2023年2月 43(2),pp.547-555 9. Naoko Kuwabara, Miho Ohta-Shimizu, Fumiko Fuwa F, Eriko Tomitsuka, Shinji Sato, Saori Nakagawa Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells. Lipids 2022年5月 57(6),pp.303-311 10. Naoko Kuwabara, Yukiko Matsuo, Tsuyoshi Ueki, Yuki Nakamura, Nanami Kase, Taisuke Okayasu, Yoshihiro Mimaki, Eiichi Tachikawa, Shinji Sato, Haruki Yamada, Saori Nakagawa Inhibitory Effect of Rhei Rhizoma Constituents on the Cortisol Production in ACTH-Stimulated Bovine Adrenal Fasciculata Cells. Traditional medicine 2022年9月 3(2),pp.10 11. Naoko Kuwabara, Ramiya Sakurazawa, Miho Ohta-Shimizu, Fumiko Fuwa, Masami Tsugita, Noriyasu Sato, Shinji Sato, Saori Nakagawa Interaction of warfarin with enteral formulas and their protein components in vitro. International Journal of Analytical Bio-Science 2022年3月 10(1),pp.1-7 12. Okamoto C, Kurone Y, Takagi C, Hitara N, Nakagawa S, Tachikawa E, Ohta S, Shimoeda S. Influence of home robots on stress relief effectiveness in communication betweem people meeting for the first time. Pharmacomerics 2022年3月 103(3/4)pp.107-114 13. Ohta-Shimizu M, Fuwa F, Tomitsuka E, Nishiwaki T, Aihara K, Sato S, Nakagawa S New inhibitory effect of Latilactobacillus sakei UONUMA on the cholesterol biosynthesis pathway in human HepG2 cells. Biol Pharm Bull 2021年4月 44(4), pp.485-493 14. Sakurai M, Kubota M, Iguchi A, Shigematsu T, Yamaguchi T, Nakagawa S, Kurahashi A, OguroY, Nishiwaki T, Aihara K, Sato S Effects of the koji amazake and its lactic acid fermentation product by Lactobacillus sakei UONUMA on defecation status in healthy volunteers with relatively few stool frequencies. Food Sci Technol Res 2019年8月 25(6), pp.853-861 15. Takagi C, Nakagawa S, Hirata N, Ohta S, Shimoeda Usefulness of aromatherapy with a stress marker aiming at complementary and alternative medicine. Journal of Pharmaceutical Health Care and Sciences 2019年8月 5(18),7pages 16. Nakajima K, Nakagawa S, Konishi T Manipulation of Plasma Dehydroepiandrosteron (DHEA) by Truffle and the Cultured Mycelium: BRM like Function of Truffles. Austin Food Sci 2019年2月 4(1), pp.1032-1033 17. Hata M, Ikeda HO, Iwai S, Iida Y, Gotoh N, Asaka I, Ikeda K, Isobe Y, Hori A, Nakagawa S, Yamato S, Arita M, Yoshimura N, Tsujikawa A Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes. Proc Natl Acad Sci USA 2018年3月 115(15), pp.3936-3941 18. Hirayama S, Nagasaka H, Nakagawa S, Takuma M, Nakacho M, Yoshifuji T, Koundou H, Tsukahara H, Morikoka I, Ishida A, Yamato S, Miida T Growth hormone activities hepatic and cerebral cholesterol metabolism in small-for-gestational age children without catch-up growth. J Clin Lipidol 2017年6月 11(4), pp.1032-1042 19. Ashihara E, Munaka T, Kimura S, Nakagawa S, Nakagawa Y, Kanai M, Hirai S, Abe H, Miida T, Yamato S, Shoji S, Maekawa T Isopentenyl Pyrophosphate Secreted from Zoledronate-Stimulated Myeloma Cells, Activates the Chemotaxis of γδT Cells. Biochem Biophys Res Commun 2015年8月 63(4), pp.650-655 20. Nakagawa S, Kuwabara N, Takamatsu Y, Shimoeda S, Ohta S, Yamato S Detection of CYP2C19 gene polymorphism from noninvasive samples by cycling probe technology. Ann Clin Biochem. 2014年9月 51(2), pp.298-300. 21. Nakagawa S, Kojima Y, Sekino K, Yamato S Effect of polyphenols on 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase activity in human hepatoma HepG2 cell extracts. Biol Pharm Bull. 2013年12月 36(12) ,pp.1902-1906. 22. Hirayama S, Nakagawa S, Soda S, Kamimura Y, Nishioka E, Ueno T, Fukushima Y, Higuchi K, Inoue M, Seino U, Ohmura H, Yamato S, Miida T Ezetimibe decreases serum oxidized cholesterol without impairing bile acid synthesis in Japanese hypercholesterolemic patients. Atherosclerosis 2013年7月 230(1), pp.48-51. 23. Nakagawa S, Kuwabara N, Kobayashi H, Shimoeda S, Ohta S, Yamato S. Simple column-switching HPLC method for determining levels of the antifungal agent micafungin in human plasma and application to patient samples. Biomed. Chromatogr. 2013年5月 27(5),pp.551-555 24. Hasegawa E, Nakagawa S, Miyate Y, Takahashi K, Ohta S, Tachikawa E, Yamato S. Inhibitory effect of protopanaxatriol ginseng metabolite M4 on the production of corticosteroids in ACTH-stimulated bovine adrenal fasciculata cells. Life Sci 2013年4月 92(12), pp.687-693. 25. Nagasaka H, Okano Y, Kimura A, Mizuochi T, Sanayama Y, Takatani T, Nakagawa S, Hasegawa E, Hirano KI, Mochizuki H, Ohura T, Ishige-Wada M, Usui H, Yorifuji T, Tsukahara H, Hirayama S, Ohtake A, Yamato S, Miida T. Oxysterol changes along with cholesterol and vitamin D changes in adult phenylketonuric patients diagnosed by newborn mass-screening. Clin Chim Acta 2013年 416, pp.54-59. 26. HasegawaE, Nakagawa S, Sato M, Tachikawa E, Yamato S. Effect of polyphenols on production of steroid hormones from human adrenocortical NCI-H295R cells. Biol Pharm Bull. 2013年2月 36(2), pp.228-237 27. Nishiyama A, Isobe H, Iwao Y, Takano T, Hung WC Taneike I, Nakagawa S, Dohmae S, Iwakura N, Yamamoto T Accumulation of staphylococcal Panton-Valentine leukocidin (PVL) in the detergent-resistant membrane microdomains (DRMs) on the target cells is essential for its cytotoxicity. FEMS Immunol. Med Microbiol 2012年 66(3),pp.343-352. 28. Isobe H, Nishiyama A, Takano T, Higuchi W, Nakagawa S, Taneike I, Fukushima Y, Yamamoto T Reduction of overall Helicobacter pylori colonization levels in the stomach of mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and Its in vitro activities against H. pylori motility and adherence.. Biosci Biotechnol Biochem. 2012年 76(4),　pp.850-852.　pp.850-852. 29. Reva I, Takano T, Higuchi W, Iwao Y, Taneike I, Nakagawa S, Ike M, Pererva OV, Tarankov AS, Agapov M, Rizhkov E, Singur O, Reva G, Potapov V, Yamamoto T. Virulence genotypes and drug resistance of Helicobacter pylori from Vladivostok, Russia: another feature in the Far East. Microbiol Immunol. 2012年3月 56(3) , pp.198-202. 30. Varynskyi BO, Nakagawa S, Yamato S HPLC-UV method of determination of pitavastatin.Part.1 Chromatographic conditions. Solid phase extraction. Precision of recovery. News of　Pharmacy 2011年4月 68(4), pp.42-44 31. Yamato S, Nakagawa S, Yamazaki N, Aketo T, Tachikawa E Simultaneous determination of pregnenolone and 17α-hydroxypregnenolone by semi-micro high-performance liquid chromatography with an immobilized cholesterol oxidase as a pre-column reactor: application to bovine adrenal fasciculata cells. J Chromatogr B 2010 878, pp. 3358-3362. 32. Shimoeda S, Nakagawa S, Kobayashi H, Yamato S, Kawano K, Ohta S Clinical significance of measuring the blood concentration of itraconazole oral solution in the field of hematology. Bio Pharm Bull 2010年11月 33(11), pp.1861-1866. 33. Yamato S, Shinohara K, Nakagawa S, Kubota A, Inamura K, Watanabe G, Hirayama S, Miida T, Ohta S. HPLC determination of ketone bodies in human plasma by precolumn derivatization with p-nitrobenzene diazonium fluoroborate. Anal Biochem 2009年1月 384(1), pp.145-150. 34. Nakagawa S, Suzuki R, Yamazaki R, Kusuhara Y, Mitsumoto S, Kobayashi H, Shimoeda S, Ohta S, Yamato S Determination of the antifungal agent voriconazole in human plasma using a simple column-switching high-performance liquid chromatography and its application to a pharmacokinetic study. Chem Pharm Bull 2008年3月 56(3), Iwakura N, Kojio S, Shibuya M, Ozaki K, Takano M, Nakayama T, Nakagawa S, Okubo T, Taneike I, Yamamoto T 35. Iwakura N, Kojio S, Shibuya M, Ozaki K, Takano M, Nakayama T, Nakagawa S, Okubo T, Taneike I, Yamamoto T. Caspase-3 Activation and Apoptosis Induction in THP-1 Human Monocytic Cells by Clinical and Environmental Isolates of Vibrio vulnificus. Acta Med Biol 2006年2月 54(2) , pp.43-50. 36. Kushiya K, Nakagawa S, Taneike I, Iwakura N, Imanishi K, Uchiyama T, Tsukada H, Gejyo F, Yamamoto T. Inhibitory effect of antimicrobial agents and anisodamine on the staphylococcal superantigenic toxin-induced overproduction of proinflammatory cytokines by human peripheral blood mononuclear cells.. J Infect Chemother. 2005年4月 11(4) ,pp.192-195 37. Takizawa Y, Taneike I, Nakagawa S, Oishi T, Nitahara Y, Iwakura N, Ozaki K, Takano M, Nakayama T, Yamamoto T. A Panton-Valentine leucocidin (PVL)-positive community-acquired Methicillin-resistant Staphylococcus aureus (MRSA) strain, another such strain carrying a multiple-drug resistance plasmid, and other more-typical PVL-negative MRSA strains found in Japan. J Clin Mcrobiol 2005年7月 43(7), pp.3356-3363. 38. Iwaya A, Nakagawa S, Iwakura N, Taneike I, Kurihara M, Kuwano T, Gondaira F, Endo M, Hatakeyama K, Yamamoto T Rapid and quantitative detection of blood Serratia marcescens by a real-time PCR assay: Its clinical application and evaluation in a mouse infection model. FEMS Microbiol Lett. 2005年7月 248(2), pp.163-170.- 39. Nakagawa S, Taneike I, Mimura D, Iwakura N, Nakayama T, Emura T, Kitatsuji M, Fujimoto A, Yamamoto T Gene sequences and specific detection for Panton-Valentine leukocidin. Biochem Biophys Res Commun. 2005年4月 328(4), pp.995-1002. 40. Nakagawa S, Kushiya K, Taneike I, Imanishi K, Uchiyama T, Yamamoto T. Specific Inhibitory Action of Anisodamine against a Staphylococcal Superantigenic Toxin, Toxic Shock Syndrome Toxin (TSST)-1, leading to down-regulation of cytokine production and blocking of TSST-1 toxicity in mice.. Clin Diag Lab Immun 2005年3月 12(3), pp.399-408. 41. Taneike I, Suzuki K, Nakagawa S, Yamamoto T. Intrafamilial spread of the same Clarithromycin-resistant Helicobacter pylori infection confirmed by molecular analysis. J Clin Microbiol 2004年8月 42(8),pp.3901-3903. 42. Nakagawa S, Kojio S, Taneike I, Iwakura N, Tamura Y, Kushiya K, Gondaira F, Yamamoto T. Inhibitory action of telithromycin against Shiga toxin and endotoxin. Biochem Biophys Res Commun. 2003年10月 310(4), pp.1194-1199. 43. Yamamoto T, Kojio S, Taneike I, Nakagawa S, Iwakura N, Wakisaka-Saito N 60Co irradiation of Shiga toxin (Stx)-producing Escherichia coli induces Stx phage. FEMS Microbiol Lett. 2003年 222, pp.141-147. 44. Takizawa Y, Shimizu T, Iwaya A, Hatakeyama K, Taneike I, Nakagawa S, Nyuzuki S, Gondaira F, Tsukada H, Gejyo F, Yamamoto T. A multiple superantigenic toxin pattern of methicillin-resistant Staphylococcus aureus (MRSA) as a risk factor in the development of toxic shock syndrome (TSS).. Acta Med Biol 2003年12月 51(4),pp.141-147. 45. Shibuya M, Ito R, Takizawa Y, Taneike I, Nakagawa S, Iwakura N, Nakayama T, Anno M, Yagi Y, Yamamoto T Occurrence of a Vibrio vulnificus infection in Niigata in 2003. Acta Med Biol. 2003年12月 51(4) , pp.149-156. 46. Takizawa Y, Taneike I, Nakagawa S, Ishii S, Kurabayashi T, Tanaka K, Gejyo F, Yamamoto T. Molecular DNA analysis of methicillin-resistant Staphylococcus aureus (MRSA) infection in a neonatal intensive care unit. Acta Med Biol 2003年9月 51(3), pp.103-109. 47. Ohara T, Kojio S, Taneike I, Nakagawa S, Gondaira F, Tamura Y, Gejyo F, Zhang H-M, Yamamoto T. Effects of azithromycin on Shiga toxin production by Escherichia coli and the subsequent host inflammatory response. Antimicrob Agents Chemother 2002年11月 46(11), pp.3478-3483. 48. Goshi S, Taneike I, Nakagawa S, Tamura Y, Ohara T, Kojio S, Ozaki K, Tsukada H, Aoki Y, Asakura H, Gejyo F, Itoh M, Yamamoto T Molecular DNA analysis of nosocomial infection by Enterobacter aerogenes in three cases of septicemia in Japan. J Hosp Infect. 2002年3月 51(3), pp.221-225. 49. Iwaya A, Nakagawa S, Iwakura N, Taneike I, Hatakeyama K, Yamamoto T Nosocomial Outbreak-Derived Serratia marcescens: Rapid and Quantitative Detection of the Agent in Blood by a Real Time PCR Assay. Acta Med Biol 2002年11月 50(4), pp.185-190. 50. Taneike I, Nakagawa S, Iwaya A, Yamamoto T Nosocomial Outbreak-Derived Serratia marcescens: In Vitro Susceptibility to Antimicrobial Agents in Comparison with Carbapenem-Resistant Strains. Acta Med Biol 2002年11月 50(4), pp.177-183.. 51. Yamamoto T, Taneike I, Tamura Y, Nakagawa S In vitro susceptibility of Bacillus anthracis to antimicrobial agents including carbapenems and fosfomycin. Acta Med Biol 2001年12月 49(3/4), pp.95-99. 52. Research　map参照
研究論文（和文）	1. 桑原直子, 清水（太田）美穂, 不破史子, 継田雅美, 佐藤則泰, 佐藤眞治, 中川沙織経腸栄養剤およびその成分による遊離フェニトイン率とフェニトインの吸収に及ぼす作用薬学雑誌 2023年1月 143, 85-94 2. 佐藤則泰、村川彩乃、西香子、本間光三、小池由博、八木和徳、継田雅美、清水 (太田)美穗、中川沙織経腸栄養剤とワルファリンの相互作用：2例の症例報告とin vitro研究日本病院薬剤師会雑誌 2020年1月 56(1)pp.41-47 3. 清水(太田) 美穂、不破　史子、中川沙織、大和　進、三井田　孝培養細胞系を用いたコレステロール異化代謝経路に対するゲニピンの作用評価臨床化学 2019年1月 48(1), pp.39-42 4. 中川　沙織 , 不破　史子, 清水 (太田)　美穗, 大和　進ダイゼインのデスモステロール経路に対する抑制効果生物試料分析 2018年3月 41(3), pp.147-152 5. 森川　剛、岡澤香津子、清水　貴裕、小田切　佐代子、不破　史子、中川　沙織、大和　進急性メタノール中毒の１例とギ酸の血中濃度分析法の検討. 日本中毒学会誌 2015年3月 28(3), pp.243-246. 6. 岡部　恵見子, 竹本　稔, 中川　沙織, 内田　大学, 大和　進, 平山　哲, 三井田　孝, 小林　一貴, 横手　幸太郎著明なアキレス腱肥厚を契機に発見された脳腱黄色腫の1例 Progress in Medicine 2013年8月 33(7), pp.1659-1661. 7. 佐藤　友美，桑原直子, 中川　沙織，大和　進選択的固相抽出前処理法を用いるイソペンテニルピロリン酸とジメチルアリルピロリン酸との合量のLC-MS/MS定量. 分析化学 2013年8月 62(8), pp.731-735 8. 中川　沙織、星　尚寛、久保　敦史、大和　進緑茶飲料中に含まれるポリフェノールの定量と茶葉の種類によるポリフェノール含量の違い. 分析化学 2013年 62(1), pp.51-55. 9. 長谷川絵梨、中川沙織、高橋香織、大和進 24S-ヒドロキシコレステロールの細胞毒性に対するポリフェノールの保護効果. 日本補完代替医療学会誌 2012年3月 9(1), pp.65-68. 10. 山﨑怜子、中川沙織、田辺顕子、池内健、三井田孝、大和進ガスクロマトグラフィー/質量分析法によるヒト脳脊髄液中の24S-ヒドロキシコレステロールの定量. 分析化学 2008年9月 57(9), pp.707-713. 11. 下枝貞彦、中澤一純、小林光、中川沙織、大和進、笹木睦子、河野健治、太田伸. 血液内科領域におけるボリコナゾール血中濃度測定の臨床的意義医療薬学 2008年7月 34(7),pp.638-643. 12. カンドレン　コンスタンチン, 長谷川　奏恵, 藤島　基宣, 中牟礼　道秀, 中川　沙織, 滝沢　陽子, 岩倉　信弘, 種池　郁恵, 山本　達男. リアルタイムPCRによる腸管出血性大腸菌の検出およびロシアと日本における腸管出血性大腸菌感染症の比較. 新潟医学会雑誌 2004年5月 118(5), pp.267-270. 13. 伊藤　岳司、坂本　泰子、篠崎洋、田島　陽介、番場　景子、吉田　邦彦、中川　沙織、種池　郁恵、小塩　精一、梅香満、山本　達男. スーパー抗原毒素によるサイトカイン異常産生のマクロライド系抗菌薬による制御. 新潟医学会雑誌 2004年2月 118, pp.118-120 14. 岩谷　昭、中川　沙織、種池　郁恵、岩倉　信弘、山本　達男、畠山　勝義、下野　和之、桑原　孝. セラチア感染と輸液投与時の衛生管理. 新潟医学会雑誌 2003年9月 117(9), pp.469-478. 15. 大津　義晃、荻野　崇之、嘉戸　槙一、山下　聡、和田　真一、種池　郁恵、中川　沙織、小塩　精一、山本　達男院内のMRSAと食中毒からの黄色ブドウ球菌の形態と病原性遺伝子分布. 新潟医学会雑誌 2002年3月 116(3) , pp.129-132.
総説・解説	1. 2023 中川　沙織（日本臨床化学会学術賞受賞報告）コレステロール合成・吸収・代謝物の高感度定量法の開発とバイオマーカーなどへの臨床応用. 臨床化学. 2024年1月 53(1),pp.37-43. 2. 2018 中川　沙織、大和　進研究者の広場　胆汁酸への代謝促進による高コレステロール血症予防. アグリバイオ. 2018年7月 2018年7月臨時増刊号2(8), pp.795-797(69-71).

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Papers	1. 2024 Daisuke Tomita, Yuuki Bamba, Naoko Kuwabara, Shota Akakabe, Yasuhiro Matsubayashi, Saori Nakagawa, Hirohito Sone, and Kei Nishiyama A Case of Concurrent Metformin-Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis. Journal of Emergency Medicine 2025年2月 inpress 2. 2024 Naoko Kuwabara, Junkichi Kanda, Shinji Sato, Saori Nakagawa Impact of daily high ergosterol intake for 14 weeks in ovariectomized rats on cholesterol and vitamin D3 biosynthesis pathways. Biol. Pharm. Bull. 2024年12月 48(1),pp.39-45 3. 2024 Yusuke Mochizuki, Nagaaki Katoh, Akira Matsushima, Masahide Yazaki, Naoko Kuwabara, Saori Nakagawa, Yoshiki Sekijima Involvement of bile acid in diarrhea and therapeutic effect of colestimide in hereditary ATTR amyloidosis. Amyloid 2024年11月 32(1),pp.39-45 4. 2023 Naoko Kuwabara, Shinji Sato, Saori Nakagawa Effects of long-term high-ergosterol intake on the cholesterol and vitamin D biosynthetic pathways of rats fed a high-fat and high-sucrose diet. Biol. Pharm. Bull. 2023年12月 46(12),pp.1683-1691 5. 2023 Naoko Kuwabara, Fumiko Fuwa, Shinji Sato, Satoshi Hirayama, Takashi Miida, Saori Nakagawa Simultaneous determination of cholesterol precursors, plant sterols, and oxysterols in plasma using one-round pretreatment. Medical Mass Spectrometry 2023年6月 7(1),pp.89-97 6. 2023 Naoko Kuwabara, Shinji Sato, Masami Tsugita, Noriyasu Sato, Saori Nakagawa Effects of enteral formulas and their food protein and dietary fiber components on postprandial plasma warfarin concentration in rats. Chromatography 2023年5月 44(2),pp.69-76 7. 2023 Kai T, Hirayama S, Soda S, Fuwa F, Nakagawa S, Ueno T, Hori A, Miida T. Higher concentration of 25-hydroxycholesterol in treatment-naïve patients with type 2 diabetes compared to healthy individuals. J Clin Lipidol 2023年4月 17,384-391 8. 2022 Yusuke Sano, Naoko Kuwabara, Saori Nakagawa, Yuki Toda, Shigekuni Hosogi, Shinji Sato, Eishi Ashihara Hypoxia-adapted multiple myeloma stem cells resist γδ-T-cell-mediated killing by modulating the mevalonate pathway. Anticancer Research 2023年2月 43(2),pp.547-555 9. 2022 Naoko Kuwabara, Miho Ohta-Shimizu, Fumiko Fuwa F, Eriko Tomitsuka, Shinji Sato, Saori Nakagawa Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells. Lipids 2022年5月 57(6),pp.303-311 10. 2022 Naoko Kuwabara, Yukiko Matsuo, Tsuyoshi Ueki, Yuki Nakamura, Nanami Kase, Taisuke Okayasu, Yoshihiro Mimaki, Eiichi Tachikawa, Shinji Sato, Haruki Yamada, Saori Nakagawa Inhibitory Effect of Rhei Rhizoma Constituents on the Cortisol Production in ACTH-Stimulated Bovine Adrenal Fasciculata Cells. Traditional medicine 2022年9月 3(2),pp.10 11. 2021 Naoko Kuwabara, Ramiya Sakurazawa, Miho Ohta-Shimizu, Fumiko Fuwa, Masami Tsugita, Noriyasu Sato, Shinji Sato, Saori Nakagawa Interaction of warfarin with enteral formulas and their protein components in vitro. International Journal of Analytical Bio-Science 2022年3月 10(1),pp.1-7 12. 2021 Okamoto C, Kurone Y, Takagi C, Hitara N, Nakagawa S, Tachikawa E, Ohta S, Shimoeda S. Influence of home robots on stress relief effectiveness in communication betweem people meeting for the first time. Pharmacomerics 2022年3月 103(3/4)pp.107-114 13. 2021 Ohta-Shimizu M, Fuwa F, Tomitsuka E, Nishiwaki T, Aihara K, Sato S, Nakagawa S New inhibitory effect of Latilactobacillus sakei UONUMA on the cholesterol biosynthesis pathway in human HepG2 cells. Biol Pharm Bull 2021年4月 44(4), pp.485-493 14. 2019 Sakurai M, Kubota M, Iguchi A, Shigematsu T, Yamaguchi T, Nakagawa S, Kurahashi A, OguroY, Nishiwaki T, Aihara K, Sato S Effects of the koji amazake and its lactic acid fermentation product by Lactobacillus sakei UONUMA on defecation status in healthy volunteers with relatively few stool frequencies. Food Sci Technol Res 2019年8月 25(6), pp.853-861 15. 2019 Takagi C, Nakagawa S, Hirata N, Ohta S, Shimoeda Usefulness of aromatherapy with a stress marker aiming at complementary and alternative medicine. Journal of Pharmaceutical Health Care and Sciences 2019年8月 5(18),7pages 16. 2018 Nakajima K, Nakagawa S, Konishi T Manipulation of Plasma Dehydroepiandrosteron (DHEA) by Truffle and the Cultured Mycelium: BRM like Function of Truffles. Austin Food Sci 2019年2月 4(1), pp.1032-1033 17. 2017 Hata M, Ikeda HO, Iwai S, Iida Y, Gotoh N, Asaka I, Ikeda K, Isobe Y, Hori A, Nakagawa S, Yamato S, Arita M, Yoshimura N, Tsujikawa A Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes. Proc Natl Acad Sci USA 2018年3月 115(15), pp.3936-3941 18. 2017 Hirayama S, Nagasaka H, Nakagawa S, Takuma M, Nakacho M, Yoshifuji T, Koundou H, Tsukahara H, Morikoka I, Ishida A, Yamato S, Miida T Growth hormone activities hepatic and cerebral cholesterol metabolism in small-for-gestational age children without catch-up growth. J Clin Lipidol 2017年6月 11(4), pp.1032-1042 19. 2015 Ashihara E, Munaka T, Kimura S, Nakagawa S, Nakagawa Y, Kanai M, Hirai S, Abe H, Miida T, Yamato S, Shoji S, Maekawa T Isopentenyl Pyrophosphate Secreted from Zoledronate-Stimulated Myeloma Cells, Activates the Chemotaxis of γδT Cells. Biochem Biophys Res Commun 2015年8月 63(4), pp.650-655 20. 2014 Nakagawa S, Kuwabara N, Takamatsu Y, Shimoeda S, Ohta S, Yamato S Detection of CYP2C19 gene polymorphism from noninvasive samples by cycling probe technology. Ann Clin Biochem. 2014年9月 51(2), pp.298-300. 21. 2013 Nakagawa S, Kojima Y, Sekino K, Yamato S Effect of polyphenols on 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase activity in human hepatoma HepG2 cell extracts. Biol Pharm Bull. 2013年12月 36(12) ,pp.1902-1906. 22. 2013 Hirayama S, Nakagawa S, Soda S, Kamimura Y, Nishioka E, Ueno T, Fukushima Y, Higuchi K, Inoue M, Seino U, Ohmura H, Yamato S, Miida T Ezetimibe decreases serum oxidized cholesterol without impairing bile acid synthesis in Japanese hypercholesterolemic patients. Atherosclerosis 2013年7月 230(1), pp.48-51. 23. 2013 Nakagawa S, Kuwabara N, Kobayashi H, Shimoeda S, Ohta S, Yamato S. Simple column-switching HPLC method for determining levels of the antifungal agent micafungin in human plasma and application to patient samples. Biomed. Chromatogr. 2013年5月 27(5),pp.551-555 24. 2013 Hasegawa E, Nakagawa S, Miyate Y, Takahashi K, Ohta S, Tachikawa E, Yamato S. Inhibitory effect of protopanaxatriol ginseng metabolite M4 on the production of corticosteroids in ACTH-stimulated bovine adrenal fasciculata cells. Life Sci 2013年4月 92(12), pp.687-693. 25. 2013 Nagasaka H, Okano Y, Kimura A, Mizuochi T, Sanayama Y, Takatani T, Nakagawa S, Hasegawa E, Hirano KI, Mochizuki H, Ohura T, Ishige-Wada M, Usui H, Yorifuji T, Tsukahara H, Hirayama S, Ohtake A, Yamato S, Miida T. Oxysterol changes along with cholesterol and vitamin D changes in adult phenylketonuric patients diagnosed by newborn mass-screening. Clin Chim Acta 2013年 416, pp.54-59. 26. 2012 HasegawaE, Nakagawa S, Sato M, Tachikawa E, Yamato S. Effect of polyphenols on production of steroid hormones from human adrenocortical NCI-H295R cells. Biol Pharm Bull. 2013年2月 36(2), pp.228-237 27. 2012 Nishiyama A, Isobe H, Iwao Y, Takano T, Hung WC Taneike I, Nakagawa S, Dohmae S, Iwakura N, Yamamoto T Accumulation of staphylococcal Panton-Valentine leukocidin (PVL) in the detergent-resistant membrane microdomains (DRMs) on the target cells is essential for its cytotoxicity. FEMS Immunol. Med Microbiol 2012年 66(3),pp.343-352. 28. 2012 Isobe H, Nishiyama A, Takano T, Higuchi W, Nakagawa S, Taneike I, Fukushima Y, Yamamoto T Reduction of overall Helicobacter pylori colonization levels in the stomach of mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and Its in vitro activities against H. pylori motility and adherence.. Biosci Biotechnol Biochem. 2012年 76(4),　pp.850-852.　pp.850-852. 29. 2011 Reva I, Takano T, Higuchi W, Iwao Y, Taneike I, Nakagawa S, Ike M, Pererva OV, Tarankov AS, Agapov M, Rizhkov E, Singur O, Reva G, Potapov V, Yamamoto T. Virulence genotypes and drug resistance of Helicobacter pylori from Vladivostok, Russia: another feature in the Far East. Microbiol Immunol. 2012年3月 56(3) , pp.198-202. 30. 2011 Varynskyi BO, Nakagawa S, Yamato S HPLC-UV method of determination of pitavastatin.Part.1 Chromatographic conditions. Solid phase extraction. Precision of recovery. News of　Pharmacy 2011年4月 68(4), pp.42-44 31. 2010 Yamato S, Nakagawa S, Yamazaki N, Aketo T, Tachikawa E Simultaneous determination of pregnenolone and 17α-hydroxypregnenolone by semi-micro high-performance liquid chromatography with an immobilized cholesterol oxidase as a pre-column reactor: application to bovine adrenal fasciculata cells. J Chromatogr B 2010 878, pp. 3358-3362. 32. 2010 Shimoeda S, Nakagawa S, Kobayashi H, Yamato S, Kawano K, Ohta S Clinical significance of measuring the blood concentration of itraconazole oral solution in the field of hematology. Bio Pharm Bull 2010年11月 33(11), pp.1861-1866. 33. 2008 Yamato S, Shinohara K, Nakagawa S, Kubota A, Inamura K, Watanabe G, Hirayama S, Miida T, Ohta S. HPLC determination of ketone bodies in human plasma by precolumn derivatization with p-nitrobenzene diazonium fluoroborate. Anal Biochem 2009年1月 384(1), pp.145-150. 34. 2007 Nakagawa S, Suzuki R, Yamazaki R, Kusuhara Y, Mitsumoto S, Kobayashi H, Shimoeda S, Ohta S, Yamato S Determination of the antifungal agent voriconazole in human plasma using a simple column-switching high-performance liquid chromatography and its application to a pharmacokinetic study. Chem Pharm Bull 2008年3月 56(3), Iwakura N, Kojio S, Shibuya M, Ozaki K, Takano M, Nakayama T, Nakagawa S, Okubo T, Taneike I, Yamamoto T 35. 2005 Iwakura N, Kojio S, Shibuya M, Ozaki K, Takano M, Nakayama T, Nakagawa S, Okubo T, Taneike I, Yamamoto T. Caspase-3 Activation and Apoptosis Induction in THP-1 Human Monocytic Cells by Clinical and Environmental Isolates of Vibrio vulnificus. Acta Med Biol 2006年2月 54(2) , pp.43-50. 36. 2005 Kushiya K, Nakagawa S, Taneike I, Iwakura N, Imanishi K, Uchiyama T, Tsukada H, Gejyo F, Yamamoto T. Inhibitory effect of antimicrobial agents and anisodamine on the staphylococcal superantigenic toxin-induced overproduction of proinflammatory cytokines by human peripheral blood mononuclear cells.. J Infect Chemother. 2005年4月 11(4) ,pp.192-195 37. 2005 Takizawa Y, Taneike I, Nakagawa S, Oishi T, Nitahara Y, Iwakura N, Ozaki K, Takano M, Nakayama T, Yamamoto T. A Panton-Valentine leucocidin (PVL)-positive community-acquired Methicillin-resistant Staphylococcus aureus (MRSA) strain, another such strain carrying a multiple-drug resistance plasmid, and other more-typical PVL-negative MRSA strains found in Japan. J Clin Mcrobiol 2005年7月 43(7), pp.3356-3363. 38. 2005 Iwaya A, Nakagawa S, Iwakura N, Taneike I, Kurihara M, Kuwano T, Gondaira F, Endo M, Hatakeyama K, Yamamoto T Rapid and quantitative detection of blood Serratia marcescens by a real-time PCR assay: Its clinical application and evaluation in a mouse infection model. FEMS Microbiol Lett. 2005年7月 248(2), pp.163-170.- 39. 2005 Nakagawa S, Taneike I, Mimura D, Iwakura N, Nakayama T, Emura T, Kitatsuji M, Fujimoto A, Yamamoto T Gene sequences and specific detection for Panton-Valentine leukocidin. Biochem Biophys Res Commun. 2005年4月 328(4), pp.995-1002. 40. 2004 Nakagawa S, Kushiya K, Taneike I, Imanishi K, Uchiyama T, Yamamoto T. Specific Inhibitory Action of Anisodamine against a Staphylococcal Superantigenic Toxin, Toxic Shock Syndrome Toxin (TSST)-1, leading to down-regulation of cytokine production and blocking of TSST-1 toxicity in mice.. Clin Diag Lab Immun 2005年3月 12(3), pp.399-408. 41. 2004 Taneike I, Suzuki K, Nakagawa S, Yamamoto T. Intrafamilial spread of the same Clarithromycin-resistant Helicobacter pylori infection confirmed by molecular analysis. J Clin Microbiol 2004年8月 42(8),pp.3901-3903. 42. 2003 Nakagawa S, Kojio S, Taneike I, Iwakura N, Tamura Y, Kushiya K, Gondaira F, Yamamoto T. Inhibitory action of telithromycin against Shiga toxin and endotoxin. Biochem Biophys Res Commun. 2003年10月 310(4), pp.1194-1199. 43. 2003 Yamamoto T, Kojio S, Taneike I, Nakagawa S, Iwakura N, Wakisaka-Saito N 60Co irradiation of Shiga toxin (Stx)-producing Escherichia coli induces Stx phage. FEMS Microbiol Lett. 2003年 222, pp.141-147. 44. 2003 Takizawa Y, Shimizu T, Iwaya A, Hatakeyama K, Taneike I, Nakagawa S, Nyuzuki S, Gondaira F, Tsukada H, Gejyo F, Yamamoto T. A multiple superantigenic toxin pattern of methicillin-resistant Staphylococcus aureus (MRSA) as a risk factor in the development of toxic shock syndrome (TSS).. Acta Med Biol 2003年12月 51(4),pp.141-147. 45. 2003 Shibuya M, Ito R, Takizawa Y, Taneike I, Nakagawa S, Iwakura N, Nakayama T, Anno M, Yagi Y, Yamamoto T Occurrence of a Vibrio vulnificus infection in Niigata in 2003. Acta Med Biol. 2003年12月 51(4) , pp.149-156. 46. 2003 Takizawa Y, Taneike I, Nakagawa S, Ishii S, Kurabayashi T, Tanaka K, Gejyo F, Yamamoto T. Molecular DNA analysis of methicillin-resistant Staphylococcus aureus (MRSA) infection in a neonatal intensive care unit. Acta Med Biol 2003年9月 51(3), pp.103-109. 47. 2002 Ohara T, Kojio S, Taneike I, Nakagawa S, Gondaira F, Tamura Y, Gejyo F, Zhang H-M, Yamamoto T. Effects of azithromycin on Shiga toxin production by Escherichia coli and the subsequent host inflammatory response. Antimicrob Agents Chemother 2002年11月 46(11), pp.3478-3483. 48. 2002 Goshi S, Taneike I, Nakagawa S, Tamura Y, Ohara T, Kojio S, Ozaki K, Tsukada H, Aoki Y, Asakura H, Gejyo F, Itoh M, Yamamoto T Molecular DNA analysis of nosocomial infection by Enterobacter aerogenes in three cases of septicemia in Japan. J Hosp Infect. 2002年3月 51(3), pp.221-225. 49. 2002 Iwaya A, Nakagawa S, Iwakura N, Taneike I, Hatakeyama K, Yamamoto T Nosocomial Outbreak-Derived Serratia marcescens: Rapid and Quantitative Detection of the Agent in Blood by a Real Time PCR Assay. Acta Med Biol 2002年11月 50(4), pp.185-190. 50. 2002 Taneike I, Nakagawa S, Iwaya A, Yamamoto T Nosocomial Outbreak-Derived Serratia marcescens: In Vitro Susceptibility to Antimicrobial Agents in Comparison with Carbapenem-Resistant Strains. Acta Med Biol 2002年11月 50(4), pp.177-183.. 51. 2001 Yamamoto T, Taneike I, Tamura Y, Nakagawa S In vitro susceptibility of Bacillus anthracis to antimicrobial agents including carbapenems and fosfomycin. Acta Med Biol 2001年12月 49(3/4), pp.95-99. 52. Research　map参照

Papers

1. 2024 Daisuke Tomita, Yuuki Bamba, Naoko Kuwabara, Shota Akakabe, Yasuhiro Matsubayashi, Saori Nakagawa, Hirohito Sone, and Kei Nishiyama A Case of Concurrent Metformin-Associated Lactic Acidosis and Euglycemic Diabetic Ketoacidosis. Journal of Emergency Medicine 2025年2月 inpress
2. 2024 Naoko Kuwabara, Junkichi Kanda, Shinji Sato, Saori Nakagawa Impact of daily high ergosterol intake for 14 weeks in ovariectomized rats on cholesterol and vitamin D3 biosynthesis pathways. Biol. Pharm. Bull. 2024年12月 48(1),pp.39-45
3. 2024 Yusuke Mochizuki, Nagaaki Katoh, Akira Matsushima, Masahide Yazaki, Naoko Kuwabara, Saori Nakagawa, Yoshiki Sekijima Involvement of bile acid in diarrhea and therapeutic effect of colestimide in hereditary ATTR amyloidosis. Amyloid 2024年11月 32(1),pp.39-45
4. 2023 Naoko Kuwabara, Shinji Sato, Saori Nakagawa Effects of long-term high-ergosterol intake on the cholesterol and vitamin D biosynthetic pathways of rats fed a high-fat and high-sucrose diet. Biol. Pharm. Bull. 2023年12月 46(12),pp.1683-1691
5. 2023 Naoko Kuwabara, Fumiko Fuwa, Shinji Sato, Satoshi Hirayama, Takashi Miida, Saori Nakagawa Simultaneous determination of cholesterol precursors, plant sterols, and oxysterols in plasma using one-round pretreatment. Medical Mass Spectrometry 2023年6月 7(1),pp.89-97
6. 2023 Naoko Kuwabara, Shinji Sato, Masami Tsugita, Noriyasu Sato, Saori Nakagawa Effects of enteral formulas and their food protein and dietary fiber components on postprandial plasma warfarin concentration in rats. Chromatography 2023年5月 44(2),pp.69-76
7. 2023 Kai T, Hirayama S, Soda S, Fuwa F, Nakagawa S, Ueno T, Hori A, Miida T. Higher concentration of 25-hydroxycholesterol in treatment-naïve patients with type 2 diabetes compared to healthy individuals. J Clin Lipidol 2023年4月 17,384-391
8. 2022 Yusuke Sano, Naoko Kuwabara, Saori Nakagawa, Yuki Toda, Shigekuni Hosogi, Shinji Sato, Eishi Ashihara Hypoxia-adapted multiple myeloma stem cells resist γδ-T-cell-mediated killing by modulating the mevalonate pathway. Anticancer Research 2023年2月 43(2),pp.547-555
9. 2022 Naoko Kuwabara, Miho Ohta-Shimizu, Fumiko Fuwa F, Eriko Tomitsuka, Shinji Sato, Saori Nakagawa Ergosterol increases 7-dehydrocholesterol, a cholesterol precursor, and decreases cholesterol in human HepG2 cells. Lipids 2022年5月 57(6),pp.303-311
10. 2022 Naoko Kuwabara, Yukiko Matsuo, Tsuyoshi Ueki, Yuki Nakamura, Nanami Kase, Taisuke Okayasu, Yoshihiro Mimaki, Eiichi Tachikawa, Shinji Sato, Haruki Yamada, Saori Nakagawa Inhibitory Effect of Rhei Rhizoma Constituents on the Cortisol Production in ACTH-Stimulated Bovine Adrenal Fasciculata Cells. Traditional medicine 2022年9月 3(2),pp.10
11. 2021 Naoko Kuwabara, Ramiya Sakurazawa, Miho Ohta-Shimizu, Fumiko Fuwa, Masami Tsugita, Noriyasu Sato, Shinji Sato, Saori Nakagawa Interaction of warfarin with enteral formulas and their protein components in vitro. International Journal of Analytical Bio-Science 2022年3月 10(1),pp.1-7
12. 2021 Okamoto C, Kurone Y, Takagi C, Hitara N, Nakagawa S, Tachikawa E, Ohta S, Shimoeda S. Influence of home robots on stress relief effectiveness in communication betweem people meeting for the first time. Pharmacomerics 2022年3月 103(3/4)pp.107-114
13. 2021 Ohta-Shimizu M, Fuwa F, Tomitsuka E, Nishiwaki T, Aihara K, Sato S, Nakagawa S New inhibitory effect of Latilactobacillus sakei UONUMA on the cholesterol biosynthesis pathway in human HepG2 cells. Biol Pharm Bull 2021年4月 44(4), pp.485-493
14. 2019 Sakurai M, Kubota M, Iguchi A, Shigematsu T, Yamaguchi T, Nakagawa S, Kurahashi A, OguroY, Nishiwaki T, Aihara K, Sato S Effects of the koji amazake and its lactic acid fermentation product by Lactobacillus sakei UONUMA on defecation status in healthy volunteers with relatively few stool frequencies. Food Sci Technol Res 2019年8月 25(6), pp.853-861
15. 2019 Takagi C, Nakagawa S, Hirata N, Ohta S, Shimoeda Usefulness of aromatherapy with a stress marker aiming at complementary and alternative medicine. Journal of Pharmaceutical Health Care and Sciences 2019年8月 5(18),7pages
16. 2018 Nakajima K, Nakagawa S, Konishi T Manipulation of Plasma Dehydroepiandrosteron (DHEA) by Truffle and the Cultured Mycelium: BRM like Function of Truffles. Austin Food Sci 2019年2月 4(1), pp.1032-1033
17. 2017 Hata M, Ikeda HO, Iwai S, Iida Y, Gotoh N, Asaka I, Ikeda K, Isobe Y, Hori A, Nakagawa S, Yamato S, Arita M, Yoshimura N, Tsujikawa A Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes. Proc Natl Acad Sci USA 2018年3月 115(15), pp.3936-3941
18. 2017 Hirayama S, Nagasaka H, Nakagawa S, Takuma M, Nakacho M, Yoshifuji T, Koundou H, Tsukahara H, Morikoka I, Ishida A, Yamato S, Miida T Growth hormone activities hepatic and cerebral cholesterol metabolism in small-for-gestational age children without catch-up growth. J Clin Lipidol 2017年6月 11(4), pp.1032-1042
19. 2015 Ashihara E, Munaka T, Kimura S, Nakagawa S, Nakagawa Y, Kanai M, Hirai S, Abe H, Miida T, Yamato S, Shoji S, Maekawa T Isopentenyl Pyrophosphate Secreted from Zoledronate-Stimulated Myeloma Cells, Activates the Chemotaxis of γδT Cells. Biochem Biophys Res Commun 2015年8月 63(4), pp.650-655
20. 2014 Nakagawa S, Kuwabara N, Takamatsu Y, Shimoeda S, Ohta S, Yamato S Detection of CYP2C19 gene polymorphism from noninvasive samples by cycling probe technology. Ann Clin Biochem. 2014年9月 51(2), pp.298-300.
21. 2013 Nakagawa S, Kojima Y, Sekino K, Yamato S Effect of polyphenols on 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase activity in human hepatoma HepG2 cell extracts. Biol Pharm Bull. 2013年12月 36(12) ,pp.1902-1906.
22. 2013 Hirayama S, Nakagawa S, Soda S, Kamimura Y, Nishioka E, Ueno T, Fukushima Y, Higuchi K, Inoue M, Seino U, Ohmura H, Yamato S, Miida T Ezetimibe decreases serum oxidized cholesterol without impairing bile acid synthesis in Japanese hypercholesterolemic patients. Atherosclerosis 2013年7月 230(1), pp.48-51.
23. 2013 Nakagawa S, Kuwabara N, Kobayashi H, Shimoeda S, Ohta S, Yamato S. Simple column-switching HPLC method for determining levels of the antifungal agent micafungin in human plasma and application to patient samples. Biomed. Chromatogr. 2013年5月 27(5),pp.551-555
24. 2013 Hasegawa E, Nakagawa S, Miyate Y, Takahashi K, Ohta S, Tachikawa E, Yamato S. Inhibitory effect of protopanaxatriol ginseng metabolite M4 on the production of corticosteroids in ACTH-stimulated bovine adrenal fasciculata cells. Life Sci 2013年4月 92(12), pp.687-693.
25. 2013 Nagasaka H, Okano Y, Kimura A, Mizuochi T, Sanayama Y, Takatani T, Nakagawa S, Hasegawa E, Hirano KI, Mochizuki H, Ohura T, Ishige-Wada M, Usui H, Yorifuji T, Tsukahara H, Hirayama S, Ohtake A, Yamato S, Miida T. Oxysterol changes along with cholesterol and vitamin D changes in adult phenylketonuric patients diagnosed by newborn mass-screening. Clin Chim Acta 2013年 416, pp.54-59.
26. 2012 HasegawaE, Nakagawa S, Sato M, Tachikawa E, Yamato S. Effect of polyphenols on production of steroid hormones from human adrenocortical NCI-H295R cells. Biol Pharm Bull. 2013年2月 36(2), pp.228-237
27. 2012 Nishiyama A, Isobe H, Iwao Y, Takano T, Hung WC Taneike I, Nakagawa S, Dohmae S, Iwakura N, Yamamoto T Accumulation of staphylococcal Panton-Valentine leukocidin (PVL) in the detergent-resistant membrane microdomains (DRMs) on the target cells is essential for its cytotoxicity. FEMS Immunol. Med Microbiol 2012年 66(3),pp.343-352.
28. 2012 Isobe H, Nishiyama A, Takano T, Higuchi W, Nakagawa S, Taneike I, Fukushima Y, Yamamoto T Reduction of overall Helicobacter pylori colonization levels in the stomach of mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and Its in vitro activities against H. pylori motility and adherence.. Biosci Biotechnol Biochem. 2012年 76(4),　pp.850-852.　pp.850-852.
29. 2011 Reva I, Takano T, Higuchi W, Iwao Y, Taneike I, Nakagawa S, Ike M, Pererva OV, Tarankov AS, Agapov M, Rizhkov E, Singur O, Reva G, Potapov V, Yamamoto T. Virulence genotypes and drug resistance of Helicobacter pylori from Vladivostok, Russia: another feature in the Far East. Microbiol Immunol. 2012年3月 56(3) , pp.198-202.
30. 2011 Varynskyi BO, Nakagawa S, Yamato S HPLC-UV method of determination of pitavastatin.Part.1 Chromatographic conditions. Solid phase extraction. Precision of recovery. News of　Pharmacy 2011年4月 68(4), pp.42-44
31. 2010 Yamato S, Nakagawa S, Yamazaki N, Aketo T, Tachikawa E Simultaneous determination of pregnenolone and 17α-hydroxypregnenolone by semi-micro high-performance liquid chromatography with an immobilized cholesterol oxidase as a pre-column reactor: application to bovine adrenal fasciculata cells. J Chromatogr B 2010 878, pp. 3358-3362.
32. 2010 Shimoeda S, Nakagawa S, Kobayashi H, Yamato S, Kawano K, Ohta S Clinical significance of measuring the blood concentration of itraconazole oral solution in the field of hematology. Bio Pharm Bull 2010年11月 33(11), pp.1861-1866.
33. 2008 Yamato S, Shinohara K, Nakagawa S, Kubota A, Inamura K, Watanabe G, Hirayama S, Miida T, Ohta S. HPLC determination of ketone bodies in human plasma by precolumn derivatization with p-nitrobenzene diazonium fluoroborate. Anal Biochem 2009年1月 384(1), pp.145-150.
34. 2007 Nakagawa S, Suzuki R, Yamazaki R, Kusuhara Y, Mitsumoto S, Kobayashi H, Shimoeda S, Ohta S, Yamato S Determination of the antifungal agent voriconazole in human plasma using a simple column-switching high-performance liquid chromatography and its application to a pharmacokinetic study. Chem Pharm Bull 2008年3月 56(3), Iwakura N, Kojio S, Shibuya M, Ozaki K, Takano M, Nakayama T, Nakagawa S, Okubo T, Taneike I, Yamamoto T
35. 2005 Iwakura N, Kojio S, Shibuya M, Ozaki K, Takano M, Nakayama T, Nakagawa S, Okubo T, Taneike I, Yamamoto T. Caspase-3 Activation and Apoptosis Induction in THP-1 Human Monocytic Cells by Clinical and Environmental Isolates of Vibrio vulnificus. Acta Med Biol 2006年2月 54(2) , pp.43-50.
36. 2005 Kushiya K, Nakagawa S, Taneike I, Iwakura N, Imanishi K, Uchiyama T, Tsukada H, Gejyo F, Yamamoto T. Inhibitory effect of antimicrobial agents and anisodamine on the staphylococcal superantigenic toxin-induced overproduction of proinflammatory cytokines by human peripheral blood mononuclear cells.. J Infect Chemother. 2005年4月 11(4) ,pp.192-195
37. 2005 Takizawa Y, Taneike I, Nakagawa S, Oishi T, Nitahara Y, Iwakura N, Ozaki K, Takano M, Nakayama T, Yamamoto T. A Panton-Valentine leucocidin (PVL)-positive community-acquired Methicillin-resistant Staphylococcus aureus (MRSA) strain, another such strain carrying a multiple-drug resistance plasmid, and other more-typical PVL-negative MRSA strains found in Japan. J Clin Mcrobiol 2005年7月 43(7), pp.3356-3363.
38. 2005 Iwaya A, Nakagawa S, Iwakura N, Taneike I, Kurihara M, Kuwano T, Gondaira F, Endo M, Hatakeyama K, Yamamoto T Rapid and quantitative detection of blood Serratia marcescens by a real-time PCR assay: Its clinical application and evaluation in a mouse infection model. FEMS Microbiol Lett. 2005年7月 248(2), pp.163-170.-
39. 2005 Nakagawa S, Taneike I, Mimura D, Iwakura N, Nakayama T, Emura T, Kitatsuji M, Fujimoto A, Yamamoto T Gene sequences and specific detection for Panton-Valentine leukocidin. Biochem Biophys Res Commun. 2005年4月 328(4), pp.995-1002.
40. 2004 Nakagawa S, Kushiya K, Taneike I, Imanishi K, Uchiyama T, Yamamoto T. Specific Inhibitory Action of Anisodamine against a Staphylococcal Superantigenic Toxin, Toxic Shock Syndrome Toxin (TSST)-1, leading to down-regulation of cytokine production and blocking of TSST-1 toxicity in mice.. Clin Diag Lab Immun 2005年3月 12(3), pp.399-408.
41. 2004 Taneike I, Suzuki K, Nakagawa S, Yamamoto T. Intrafamilial spread of the same Clarithromycin-resistant Helicobacter pylori infection confirmed by molecular analysis. J Clin Microbiol 2004年8月 42(8),pp.3901-3903.
42. 2003 Nakagawa S, Kojio S, Taneike I, Iwakura N, Tamura Y, Kushiya K, Gondaira F, Yamamoto T. Inhibitory action of telithromycin against Shiga toxin and endotoxin. Biochem Biophys Res Commun. 2003年10月 310(4), pp.1194-1199.
43. 2003 Yamamoto T, Kojio S, Taneike I, Nakagawa S, Iwakura N, Wakisaka-Saito N 60Co irradiation of Shiga toxin (Stx)-producing Escherichia coli induces Stx phage. FEMS Microbiol Lett. 2003年 222, pp.141-147.
44. 2003 Takizawa Y, Shimizu T, Iwaya A, Hatakeyama K, Taneike I, Nakagawa S, Nyuzuki S, Gondaira F, Tsukada H, Gejyo F, Yamamoto T. A multiple superantigenic toxin pattern of methicillin-resistant Staphylococcus aureus (MRSA) as a risk factor in the development of toxic shock syndrome (TSS).. Acta Med Biol 2003年12月 51(4),pp.141-147.
45. 2003 Shibuya M, Ito R, Takizawa Y, Taneike I, Nakagawa S, Iwakura N, Nakayama T, Anno M, Yagi Y, Yamamoto T Occurrence of a Vibrio vulnificus infection in Niigata in 2003. Acta Med Biol. 2003年12月 51(4) , pp.149-156.
46. 2003 Takizawa Y, Taneike I, Nakagawa S, Ishii S, Kurabayashi T, Tanaka K, Gejyo F, Yamamoto T. Molecular DNA analysis of methicillin-resistant Staphylococcus aureus (MRSA) infection in a neonatal intensive care unit. Acta Med Biol 2003年9月 51(3), pp.103-109.
47. 2002 Ohara T, Kojio S, Taneike I, Nakagawa S, Gondaira F, Tamura Y, Gejyo F, Zhang H-M, Yamamoto T. Effects of azithromycin on Shiga toxin production by Escherichia coli and the subsequent host inflammatory response. Antimicrob Agents Chemother 2002年11月 46(11), pp.3478-3483.
48. 2002 Goshi S, Taneike I, Nakagawa S, Tamura Y, Ohara T, Kojio S, Ozaki K, Tsukada H, Aoki Y, Asakura H, Gejyo F, Itoh M, Yamamoto T Molecular DNA analysis of nosocomial infection by Enterobacter aerogenes in three cases of septicemia in Japan. J Hosp Infect. 2002年3月 51(3), pp.221-225.
49. 2002 Iwaya A, Nakagawa S, Iwakura N, Taneike I, Hatakeyama K, Yamamoto T Nosocomial Outbreak-Derived Serratia marcescens: Rapid and Quantitative Detection of the Agent in Blood by a Real Time PCR Assay. Acta Med Biol 2002年11月 50(4), pp.185-190.
50. 2002 Taneike I, Nakagawa S, Iwaya A, Yamamoto T Nosocomial Outbreak-Derived Serratia marcescens: In Vitro Susceptibility to Antimicrobial Agents in Comparison with Carbapenem-Resistant Strains. Acta Med Biol 2002年11月 50(4), pp.177-183..
51. 2001 Yamamoto T, Taneike I, Tamura Y, Nakagawa S In vitro susceptibility of Bacillus anthracis to antimicrobial agents including carbapenems and fosfomycin. Acta Med Biol 2001年12月 49(3/4), pp.95-99.
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